TY - JOUR AU - Ripoll, Consuelo AU - Herrero-Foncubierta, Pilar AU - Puente-Muñoz, Virginia AU - Gonzalez-Garcia, M. Carmen AU - Miguel, Delia AU - Resa, Sandra AU - Paredes, Jose M. AU - Ruedas-Rama, Maria J. AU - Garcia-Fernandez, Emilio AU - Roldan, Mar AU - Rocha, Susana AU - De Keersmaecker, Herlinde AU - Hofkens, Johan AU - Martin, Miguel AU - Cuerva, Juan M. AU - Orte, Angel PY - 2021 DO - 10.3390/pharmaceutics13020254 UR - http://hdl.handle.net/10668/3874 T2 - Pharmaceutics AB - Recently, it was proposed that the thiophene ring is capable of promoting mitochondrial accumulation when linked to fluorescent markers. As a noncharged group, thiophene presents several advantages from a synthetic point of view, making it easier to... LA - en PB - MDPI KW - Antitumor agents KW - Fluorescence lifetime imaging KW - Medicinal chemistry KW - Metabolic drug KW - Mitochondrial carrier KW - Antineoplásicos KW - Química farmacéutica KW - Activación metabólica KW - Tiofenos KW - Mitocondrias KW - Medical Subject Headings::Disciplines and Occupations::Natural Science Disciplines::Biological Science Disciplines::Pharmacology::Chemistry, Pharmaceutical KW - Medical Subject Headings::Anatomy::Cells::Cellular Structures::Intracellular Space::Cytoplasm::Cytoplasmic Structures::Organelles::Mitochondria KW - Medical Subject Headings::Chemicals and Drugs::Organic Chemicals::Sulfur Compounds::Thiophenes KW - Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Therapeutic Uses::Antineoplastic Agents KW - Medical Subject Headings::Phenomena and Processes::Metabolic Phenomena::Metabolism TI - Chimeric Drug Design with a Noncharged Carrier for Mitochondrial Delivery TY - research article ER -