TY - JOUR AU - Saez-Atienzar, Sara AU - Bandres-Ciga, Sara AU - Langston, Rebekah G AU - Kim, Jonggeol J AU - Choi, Shing Wan AU - Reynolds, Regina H AU - Abramzon, Yevgeniya AU - Dewan, Ramita AU - Ahmed, Sarah AU - Landers, John E AU - Chia, Ruth AU - Ryten, Mina AU - Cookson, Mark R AU - Nalls, Michael A AU - ChiĆ², Adriano AU - Traynor, Bryan J PY - 2020 DO - 10.1126/sciadv.abd9036 UR - http://hdl.handle.net/10668/17080 T2 - Science advances AB - Despite the considerable progress in unraveling the genetic causes of amyotrophic lateral sclerosis (ALS), we do not fully understand the molecular mechanisms underlying the disease. We analyzed genome-wide data involving 78,500 individuals using a... LA - en PB - Public Library of Science KW - Amyotrophic Lateral Sclerosis KW - Genetic Testing KW - Genome-Wide Association Study KW - Humans KW - Polymorphism, Single Nucleotide KW - MAP-kinase-activated kinase 3 KW - Genetic Risk Score KW - Amyotrophic Lateral Sclerosis KW - Ribonucleotides KW - Mendelian Randomization Analysis KW - RNA-Seq KW - Signal Transduction KW - Genomics KW - Morphogenesis KW - Oligodendroglia TI - Genetic analysis of amyotrophic lateral sclerosis identifies contributing pathways and cell types. TY - research article VL - 7 ER -