RT Journal Article
T1 Differential Bioaccumulation Patterns of α, β-Hexachlorobenzene and Dicofol in Adipose Tissue from the GraMo Cohort (Southern Spain).
A1 Salcedo-Bellido, Inmaculada
A1 Amaya, Esperanza
A1 Perez-Diaz, Celia
A1 Soler, Anabel
A1 Vela-Soria, Fernando
A1 Requena, Pilar
A1 Barrios-Rodriguez, Rocio
A1 Echeverria, Ruth
A1 Perez-Carrascosa, Francisco M
A1 Quesada-Jimenez, Raquel
A1 Martin-Olmedo, Piedad
A1 Arrebola, Juan Pedro
K1 dicofol
K1 exposure assessment
K1 human adipose tissue
K1 predictors
K1 α-hexachlorocyclohexane
K1 β-hexachlorocyclohexane
AB To identify bioaccumulation patterns of α-, β- hexachlorocyclohexane (HCH) and dicofol in relation to sociodemographic, dietary, and lifestyle factors, adipose tissue samples of 387 subjects from GraMo cohort in Southern Spain were analyzed. Potential predictors of these organochlorine pesticides (OCP) levels were collected by face-to-face interviews and assessed by multivariable linear and logistic regression. OCPs were detected in 84.2% (β-HCH), 21.7% (α-HCH), and 19.6% (dicofol) of the population. β-HCH levels were positively related to age, body mass index (BMI), mother's occupation in agriculture during pregnancy, living in Poniente and Alpujarras, white fish, milk and water consumption, and negatively related to being male, living near to an agricultural area, working ≥10 years in agriculture, and beer consumption. Detectable α-HCH levels were positively related to age, BMI, milk consumption, mother's occupation in agriculture during pregnancy, and negatively with residence in Poniente and Alpujarras, Granada city, and Granada Metropolitan Area. Residence near to an agricultural area, smoking habit, white fish and water consumption, and living in Poniente and Alpujarras, Granada city and Granada Metropolitan Area were negatively associated with detectable dicofol levels. Our study revealed different bioaccumulation patterns of α, β-HCH and dicofol, probably due to their dissimilar period of use, and emphasize the need for assessing the exposure to frequently overlooked pollutants.
PB MDPI AG
YR 2022
FD 2022-03-08
LK http://hdl.handle.net/10668/21044
UL http://hdl.handle.net/10668/21044
LA en
NO Salcedo-Bellido I, Amaya E, Pérez-Díaz C, Soler A, Vela-Soria F, et al. Differential Bioaccumulation Patterns of α, β-Hexachlorobenzene and Dicofol in Adipose Tissue from the GraMo Cohort (Southern Spain). Int J Environ Res Public Health. 2022 Mar 11;19(6):3344.
DS RISalud
RD Apr 7, 2025