RT Journal Article T1 Dietary Inflammatory Index, Dietary Non-Enzymatic Antioxidant Capacity, and Colorectal and Breast Cancer Risk (MCC-Spain Study). A1 Obon-Santacana, Mireia A1 Romaguera, Dora A1 Gracia-Lavedan, Esther A1 Molinuevo, Amaia A1 Molina-Montes, Esther A1 Shivappa, Nitin A1 Hebert, James R A1 Tardon, Adonina A1 Castaño-Vinyals, Gemma A1 Moratalla, Ferran A1 Guino, Elisabet A1 Marcos-Gragera, Rafael A1 Azpiri, Mikel A1 Gil, Leire A1 Olmedo-Requena, Rocio A1 Lozano-Lorca, Macarena A1 Alguacil, Juan A1 Fernandez-Villa, Tania A1 Martin, Vicente A1 Molina, Antonio J A1 Ederra, Maria A1 Moreno-Iribas, Conchi A1 Perez, Beatriz A1 Aragones, Nuria A1 Castello, Adela A1 Huerta, Jose Mª A1 Dierssen-Sotos, Trinidad A1 Gomez-Acebo, Ines A1 Molina-Barcelo, Ana A1 Pollan, Marina A1 Kogevinas, Manolis A1 Moreno, Victor A1 Amiano, Pilar K1 MCC-Spain K1 NEAC K1 antioxidants K1 breast cancer K1 case-control study K1 colorectal cancer K1 diet K1 dietary inflammatory index AB Inflammation and antioxidant capacity have been associated with colorectal and breast cancer. We computed the dietary inflammatory index (DII®), and the total dietary non-enzymatic antioxidant capacity (NEAC) and associated them with colorectal and breast cancer risk in the population-based multi case-control study in Spain (MCC-Spain). We included 1852 colorectal cancer and 1567 breast cancer cases, and 3447 and 1486 population controls, respectively. DII score and NEAC were derived using data from a semi-quantitative validated food frequency questionnaire. Unconditional logistic regression models were used to estimate odds ratios (OR) and 95% confidence intervals (95%CI) for energy-adjusted DII (E-DII), and a score combining E-DII and NEAC. E-DII was associated with colorectal cancer risk (OR = 1.93, highest quartile versus lowest, 95%CI:1.60-2.32; p-trend: 0.10). The combined score of high E-DII scores and low antioxidant values were associated with colorectal cancer risk (OR = 1.48, highest quartile versus lowest, 95%CI: 1.26-1.74; p-trend: PB MDPI AG YR 2019 FD 2019-06-19 LK http://hdl.handle.net/10668/14166 UL http://hdl.handle.net/10668/14166 LA en NO Obón-Santacana M, Romaguera D, Gracia-Lavedan E, Molinuevo A, Molina-Montes E, Shivappa N, et al. Dietary Inflammatory Index, Dietary Non-Enzymatic Antioxidant Capacity, and Colorectal and Breast Cancer Risk (MCC-Spain Study). Nutrients. 2019 Jun 21;11(6):1406. DS RISalud RD Apr 11, 2025