%0 Journal Article
%A Obon-Santacana, Mireia
%A Romaguera, Dora
%A Gracia-Lavedan, Esther
%A Molinuevo, Amaia
%A Molina-Montes, Esther
%A Shivappa, Nitin
%A Hebert, James R
%A Tardon, Adonina
%A Castaño-Vinyals, Gemma
%A Moratalla, Ferran
%A Guino, Elisabet
%A Marcos-Gragera, Rafael
%A Azpiri, Mikel
%A Gil, Leire
%A Olmedo-Requena, Rocio
%A Lozano-Lorca, Macarena
%A Alguacil, Juan
%A Fernandez-Villa, Tania
%A Martin, Vicente
%A Molina, Antonio J
%A Ederra, Maria
%A Moreno-Iribas, Conchi
%A Perez, Beatriz
%A Aragones, Nuria
%A Castello, Adela
%A Huerta, Jose Mª
%A Dierssen-Sotos, Trinidad
%A Gomez-Acebo, Ines
%A Molina-Barcelo, Ana
%A Pollan, Marina
%A Kogevinas, Manolis
%A Moreno, Victor
%A Amiano, Pilar
%T Dietary Inflammatory Index, Dietary Non-Enzymatic Antioxidant Capacity, and Colorectal and Breast Cancer Risk (MCC-Spain Study).
%D 2019
%U http://hdl.handle.net/10668/14166
%X Inflammation and antioxidant capacity have been associated with colorectal and breast cancer. We computed the dietary inflammatory index (DII®), and the total dietary non-enzymatic antioxidant capacity (NEAC) and associated them with colorectal and breast cancer risk in the population-based multi case-control study in Spain (MCC-Spain). We included 1852 colorectal cancer and 1567 breast cancer cases, and 3447 and 1486 population controls, respectively. DII score and NEAC were derived using data from a semi-quantitative validated food frequency questionnaire. Unconditional logistic regression models were used to estimate odds ratios (OR) and 95% confidence intervals (95%CI) for energy-adjusted DII (E-DII), and a score combining E-DII and NEAC. E-DII was associated with colorectal cancer risk (OR = 1.93, highest quartile versus lowest, 95%CI:1.60-2.32; p-trend: 0.10). The combined score of high E-DII scores and low antioxidant values were associated with colorectal cancer risk (OR = 1.48, highest quartile versus lowest, 95%CI: 1.26-1.74; p-trend:
%K MCC-Spain
%K NEAC
%K antioxidants
%K breast cancer
%K case-control study
%K colorectal cancer
%K diet
%K dietary inflammatory index
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