RT Journal Article T1 Shunt Overdrainage: Reappraisal of the Syndrome and Proposal for an Integrative Model. A1 Ros, Bienvenido A1 Iglesias, Sara A1 Linares, Jorge A1 Cerro, Laura A1 Casado, Julia A1 Arráez, Miguel Angel K1 antisiphon device K1 craniocerebral disproportion K1 gravitational valves K1 pathophysiology K1 shunt overdrainage K1 siphoning K1 slit ventricle syndrome AB Although shunt overdrainage is a well-known complication in hydrocephalus management, the problem has been underestimated. Current literature suggests that the topic requires more examination. An insight into this condition is limited by a lack of universally agreed-upon diagnostic criteria, heterogeneity of published series, the multitude of different management options and misunderstanding of relationships among pathophysiological mechanisms involved. We carried out a review of the literature on clinical, radiological, intracranial pressure (ICP), pathophysiological and treatment concepts to finally propose an integrative model. Active prophylaxis and management are proposed according to this model based on determination of pathophysiological mechanisms and predisposing factors behind each individual case. As pathophysiology is progressively multifactorial, prevention of siphoning with gravitational valves or antisiphon devices is mandatory to avoid or minimize further complications. Shunt optimization or transferal and neuroendoscopy may be recommended when ventricular collapse and cerebrospinal fluid isolation appear. Cranial expansion may be useful in congenital or acquired craniocerebral disproportion and shunting the subarachnoid space in communicating venous hydrocephalus and idiopathic intracranial hypertension. SN 2077-0383 YR 2021 FD 2021-08-17 LK http://hdl.handle.net/10668/18439 UL http://hdl.handle.net/10668/18439 LA en DS RISalud RD Apr 8, 2025