TY - JOUR AU - Gridelli, Cesare AU - Ciuleanu, Tudor AU - Domine, Manuel AU - Szczesna, Aleksandra AU - Bover, Isabel AU - Cobo, Manuel AU - Kentepozidis, Nikolaos AU - Zarogoulidis, Konstantinos AU - Kalofonos, Charalabos AU - Kazarnowisz, Andrzej AU - Korozan, Magdalena AU - de-Las-Penas, Ramon AU - Majem, Margarita AU - Chella, Antonio AU - Griesinger, Frank AU - Bournakis, Evangelos AU - Sadjadian, Parvis AU - Kotsakis, Athanasios AU - Chinet, Thierry AU - Syrigos, Kostantinos N AU - Correale, Pierpaolo AU - Gallou, Catherine AU - Jamet, Jeanne- Menez AU - Vetsika, Eleni- Kyriaki AU - Kosmatopoulos, Kostas AU - Georgoulias, Vassilis PY - 2020 DO - 10.1038/s41416-020-0785-y UR - http://hdl.handle.net/10668/15282 T2 - British journal of cancer AB - The cancer vaccine Vx-001, which targets the universal tumour antigen TElomerase Reverse Transcriptase (TERT), can mount specific Vx-001/TERT572 CD8 + cytotoxic T cells; this immune response is associated with improved overall survival (OS) in... LA - en PB - Nature Publishing Group KW - CD8-Positive T-Lymphocytes KW - Cancer Vaccines KW - Carcinoma, Non-Small-Cell Lung KW - Aged KW - Female KW - Humans KW - Immunity KW - Immunotherapy KW - Maintenance Chemotherapy KW - Male KW - Middle Aged KW - Neoplasm Staging KW - Placebo Effect KW - Telomerase TI - Clinical activity of a htert (vx-001) cancer vaccine as post-chemotherapy maintenance immunotherapy in patients with stage IV non-small cell lung cancer: final results of a randomised phase 2 clinical trial. TY - research article VL - 122 ER -