%0 Journal Article
%A Fonte, Luis
%A Acosta, Armando
%A Sarmiento, María E
%A Norazmi, Mohd Nor
%A Ginori, María
%A de Armas, Yaxsier
%A Calderón, Enrique J
%T Overlapping of Pulmonary Fibrosis of Postacute COVID-19 Syndrome and Tuberculosis in the Helminth Coinfection Setting in Sub-Saharan Africa.
%D 2022
%U http://hdl.handle.net/10668/21595
%X There is an increasing attention to the emerging health problem represented by the clinical and functional long-term consequences of SARS-CoV-2 infection, referred to as postacute COVID-19 syndrome. Clinical, radiographic, and autopsy findings have shown that a high rate of fibrosis and restriction of lung function are present in patients who have recovered from COVID-19. Patients with active TB, or those who have recovered from it, have fibrotic scarred lungs and, consequently, some degree of impaired respiratory function. Helminth infections trigger predominantly type 2 immune responses and the release of regulatory and fibrogenic cytokines, such as TGF-β. Here, we analyze the possible consequences of the overlapping of pulmonary fibrosis secondary to COVID-19 and tuberculosis in the setting of sub-Saharan Africa, the region of the world with the highest prevalence of helminth infection.
%K helminth coinfection
%K postacute COVID-19 syndrome
%K pulmonary fibrosis
%K sub-Saharan Africa
%K tuberculosis
%~