RT Journal Article
T1 The Fluid Aspect of the Mediterranean Diet in the Prevention and Management of Cardiovascular Disease and Diabetes: The Role of Polyphenol Content in Moderate Consumption of Wine and Olive Oil.
A1 Ditano-Vazquez, Paola
A1 Torres-Peña, Jose David
A1 Galeano-Valle, Francisco
A1 Perez-Caballero, Ana Isabel
A1 Demelo-Rodriguez, Pablo
A1 Lopez-Miranda, Jose
A1 Katsiki, Niki
A1 Delgado-Lista, Javier
A1 Alvarez-Sala-Walther, Luis A
K1 Cardiovascular disease
K1 Diabetes
K1 Mediterranean diet
K1 Olive oil
K1 Polyphenols
K1 Wine
AB A growing interest has emerged in the beneficial effects of plant-based diets for the prevention of cardiovascular disease, diabetes and obesity. The Mediterranean diet, one of the most widely evaluated dietary patterns in scientific literature, includes in its nutrients two fluid foods: olive oil, as the main source of fats, and a low-to-moderate consumption of wine, mainly red, particularly during meals. Current mechanisms underlying the beneficial effects of the Mediterranean diet include a reduction in inflammatory and oxidative stress markers, improvement in lipid profile, insulin sensitivity and endothelial function, as well as antithrombotic properties. Most of these effects are attributable to bioactive ingredients including polyphenols, mono- and poly-unsaturated fatty acids. Polyphenols are a heterogeneous group of phytochemicals containing phenol rings. The principal classes of red wine polyphenols include flavonols (quercetin and myricetin), flavanols (catechin and epicatechin), anthocyanin and stilbenes (resveratrol). Olive oil has at least 30 phenolic compounds. Among them, the main are simple phenols (tyrosol and hydroxytyrosol), secoroids and lignans. The present narrative review focuses on phenols, part of red wine and virgin olive oil, discussing the evidence of their effects on lipids, blood pressure, atheromatous plaque and glucose metabolism.
PB MDPI
YR 2019
FD 2019-11-13
LK http://hdl.handle.net/10668/14727
UL http://hdl.handle.net/10668/14727
LA en
NO Ditano-Vázquez P, Torres-Peña JD, Galeano-Valle F, Pérez-Caballero AI, Demelo-Rodríguez P, Lopez-Miranda J, et al. The Fluid Aspect of the Mediterranean Diet in the Prevention and Management of Cardiovascular Disease and Diabetes: The Role of Polyphenol Content in Moderate Consumption of Wine and Olive Oil. Nutrients. 2019 Nov 19;11(11):2833
DS RISalud
RD Mar 14, 2025