TY - JOUR AU - Díaz-Beyá, Marina AU - Brunet, Salut AU - Nomdedéu, Josep AU - Pratcorona, Marta AU - Cordeiro, Anna AU - Gallardo, David AU - Escoda, Lourdes AU - Tormo, Mar AU - Heras, Inmaculada AU - Ribera, Josep María AU - Duarte, Rafael AU - Queipo de Llano, María Paz AU - Bargay, Joan AU - Sampol, Antonia AU - Nomdedéu, Meritxell AU - Risueño, Ruth M AU - Hoyos, Montserrat AU - Sierra, Jorge AU - Monzo, Mariano AU - Navarro, Alfons AU - Esteve, Jordi PY - 2015 DO - 10.18632/oncotarget.5148 UR - http://hdl.handle.net/10668/2065 T2 - Oncotarget AB - Long non-coding RNAs (lncRNAs) are deregulated in several tumors, although their role in acute myeloid leukemia (AML) is mostly unknown.We have examined the expression of the lncRNA HOX antisense intergenic RNA myeloid 1 (HOTAIRM1) in 241 AML... LA - en PB - Impact Journals KW - Leucemia mieloide aguda KW - Leucemia promielocítica aguda KW - MicroARNs KW - Pronóstico KW - ARN no traducido KW - Recurrencia KW - Genómica KW - Humanos KW - lincRNA KW - AML KW - HOTAIRM KW - HOX KW - lncRNA KW - Medical Subject Headings::Diseases::Neoplasms::Neoplasms by Histologic Type::Leukemia::Leukemia, Myeloid::Leukemia, Myeloid, Acute KW - Medical Subject Headings::Diseases::Neoplasms::Neoplasms by Histologic Type::Leukemia::Leukemia, Myeloid::Leukemia, Myeloid, Acute::Leukemia, Promyelocytic, Acute KW - Medical Subject Headings::Chemicals and Drugs::Nucleic Acids, Nucleotides, and Nucleosides::Antisense Elements (Genetics)::RNA, Antisense::MicroRNAs KW - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Prognosis KW - Medical Subject Headings::Chemicals and Drugs::Nucleic Acids, Nucleotides, and Nucleosides::Nucleic Acids::RNA::RNA, Untranslated KW - Medical Subject Headings::Diseases::Pathological Conditions, Signs and Symptoms::Pathologic Processes::Disease Attributes::Recurrence KW - Medical Subject Headings::Disciplines and Occupations::Natural Science Disciplines::Biological Science Disciplines::Biology::Genetics::Genomics KW - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans TI - The lincRNA HOTAIRM1, located in the HOXA genomic region, is expressed in acute myeloid leukemia, impacts prognosis in patients in the intermediate-risk cytogenetic category, and is associated with a distinctive microRNA signature. TY - research article ER -