TY  - JOUR
AU  - Amanat, Sana
AU  - Gallego-Martinez, Alvaro
AU  - Sollini, Joseph
AU  - Perez-Carpena, Patricia
AU  - Espinosa-Sanchez, Juan M.
AU  - Aran, Ismael
AU  - Soto-Varela, Andres
AU  - Batuecas-Caletrio, Angel
AU  - Canlon, Barbara
AU  - May, Patrick
AU  - Cederroth, Christopher R.
AU  - Lopez-Escamez, Jose A.
PY  - 2021
DO  - 10.1016/j.ebiom.2021.103309
UR  - http://hdl.handle.net/10668/4136
T2  - EBioMedicine
AB  - tinnitus is a heterogeneous condition associated with audiological and/or mental disorders. Chronic, severe tinnitus is reported in 1% of the population and it shows a relevant heritability, according to twins, adoptees and familial aggregation...
LA  - en
PB  - Elsevier B.V.
KW  - Tinnitus
KW  - Extreme phenotype
KW  - Axon initial segment
KW  - Exome sequencing
KW  - Meniere disease
KW  - Epilepsy
KW  - Genetic studies
KW  - Acúfeno
KW  - Fenotipo
KW  - Segmento inicial del axón
KW  - Secuenciación del exoma completo
KW  - Enfermedad de Meniere
KW  - Epilepsia
KW  - Estudios de asociación genética
KW  - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Structures::Genome::Genome Components::Genes::Alleles
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals
KW  - Medical Subject Headings::Anatomy::Nervous System::Central Nervous System::Brain
KW  - Medical Subject Headings::Disciplines and Occupations::Natural Science Disciplines::Biological Science Disciplines::Biology::Computational Biology
KW  - Medical Subject Headings::Check Tags::Female
KW  - Medical Subject Headings::Disciplines and Occupations::Natural Science Disciplines::Biological Science Disciplines::Biology::Genetics::Genetic Research::Gene Ontology
KW  - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Genetic Techniques::Genetic Association Studies
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
KW  - Medical Subject Headings::Check Tags::Male
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Mice
KW  - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Phenotype
KW  - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Data Collection::Health Surveys::Health Status Indicators::Patient Acuity::Severity of Illness Index
KW  - Medical Subject Headings::Geographical Locations::Geographic Locations::Europe::Scandinavia::Sweden
KW  - Medical Subject Headings::Anatomy::Nervous System::Synapses
KW  - Medical Subject Headings::Diseases::Otorhinolaryngologic Diseases::Ear Diseases::Hearing Disorders::Tinnitus
KW  - Medical Subject Headings::Diseases::Pathological Conditions, Signs and Symptoms::Pathologic Processes::Disease Attributes::Disease Susceptibility::Genetic Predisposition to Disease
KW  - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Variation
KW  - Medical Subject Headings::Diseases::Otorhinolaryngologic Diseases::Ear Diseases::Labyrinth Diseases::Endolymphatic Hydrops::Meniere Disease
KW  - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Data Collection::Questionnaires::Self Report
KW  - Medical Subject Headings::Diseases::Nervous System Diseases::Central Nervous System Diseases::Brain Diseases::Epilepsy::Epilepsy, Generalized
KW  - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Cytoskeletal Proteins
KW  - Medical Subject Headings::Phenomena and Processes::Biological Phenomena
KW  - Medical Subject Headings::Psychiatry and Psychology::Mental Disorders
KW  - Medical Subject Headings::Disciplines and Occupations::Natural Science Disciplines::Biological Science Disciplines::Biology::Genetics::Genomics
KW  - Medical Subject Headings::Anatomy::Nervous System::Neurons
TI  - Burden of rare variants in synaptic genes in patients with severe tinnitus: An exome based extreme phenotype study
TY  - research article
ER  -