TY  - JOUR
AU  - García-Benítez, Francisco
AU  - Gaillard, Hélène
AU  - Aguilera, Andrés
PY  - 2017
DO  - 10.1073/pnas.1707845114
UR  - http://hdl.handle.net/10668/11645
T2  - Proceedings of the National Academy of Sciences of the United States of America
AB  - During transcription, the mRNA may hybridize with DNA, forming an R loop, which can be physiological or pathological, constituting in this case a source of genomic instability. To understand the mechanism by which eukaryotic cells prevent harmful R...
LA  - en
KW  - Mpl1/2
KW  - R loop
KW  - genome instability
KW  - nuclear pores
KW  - transcription
KW  - Chromatin
KW  - Cytidine Deaminase
KW  - DNA Replication
KW  - DNA, Fungal
KW  - Genomic Instability
KW  - Humans
KW  - Nuclear Pore
KW  - Nuclear Proteins
KW  - Saccharomyces cerevisiae
KW  - Saccharomyces cerevisiae Proteins
KW  - Transcription, Genetic
TI  - Physical proximity of chromatin to nuclear pores prevents harmful R loop accumulation contributing to maintain genome stability.
TY  - research article
VL  - 114
ER  -