RT Journal Article
T1 In-hospital outcomes of mechanical complications in acute myocardial infarction: Analysis from a nationwide Spanish database.
A1 Sanmartín-Fernández, Marcelo
A1 Raposeiras-Roubin, Sergio
A1 Anguita-Sánchez, Manuel
A1 Marín, Francisco
A1 Garcia-Marquez, María
A1 Fernández-Pérez, Cristina
A1 Bernal-Sobrino, Jose-Luis
A1 Elola-Somoza, Francisco Javier
A1 Bueno, Héctor
A1 Cequier, Ángel
K1 cardiac tamponade
K1 mechanical complications
K1 myocardial infarction
K1 papillary muscle rupture
K1 ventricular septal rupture
AB Mechanical complications represent an important cause of mortality in myocardial infarction (MI) patients. This is a nationwide study performed to evaluate possible changes in epidemiology or prognosis of these complications with current available strategies. Information was obtained from the minimum basis data set of the Spanish National Health System, including all hospitalizations for acute myocardial infarction (AMI) from 2010 to 2015. Risk-standardized in-hospital mortality ratio was calculated using multilevel risk adjustment models. A total of 241,760 AMI episodes were analyzed, MI mechanical complications were observed in 842 patients: cardiac tamponade in 587, ventricular septal rupture in 126, and mitral regurgitation due to papillary muscle or chordae tendineae rupture in 155 (there was more than one complication in 21 patients). In-hospital mortality was 59.5%. On multivariate adjustment, variables with significant impact on in-hospital mortality were: age (OR 1.06; 95% CI 1.04-1.07; p  Mechanical complications occur in 3.5 per thousand AMI, with no significant trends to better survival over the past few years. Advanced age, cardiogenic shock and cardio-respiratory failure are the most important risk factors for in-hospital mortality. Higher experience and specialized cardiac intensive care units are associated with better outcomes.
YR 2020
FD 2020-12-21
LK http://hdl.handle.net/10668/16828
UL http://hdl.handle.net/10668/16828
LA en
DS RISalud
RD Apr 6, 2025