RT Journal Article
T1 What's in a name? Molecular subclassification of sarcomas creates fresh challenges.
A1 Díaz-Martín, Juan
A1 Biscuola, Michele
A1 Benoit, Jonatan
A1 Marcilla, David
A1 Civantos, Gema
A1 de Álava, Enrique
K1 gene fusion
K1 sarcoma
K1 transcriptomics
K1 tumor classification
AB This commentary addresses the issue of the classification of sarcomas in the article written by Watson and colleagues published recently in this journal. The article delves into the molecular characterization and distinct phenotypes of some recently described entities (e.g. BCOR-rearranged sarcomas, CIC-fused sarcomas) and describes new groups with common characteristics. This commentary focuses on several questions raised in the article, such as what makes a group of sarcomas become a clinical entity, which should be the main driver of sarcoma classification, how the classification of small round cell sarcomas is expected to evolve and how high-throughput techniques could be applied to sarcoma diagnosis in the short term. Copyright © 2018 Pathological Society of Great Britain and Ireland. Published by John Wiley & Sons, Ltd.
YR 2019
FD 2019-01-16
LK http://hdl.handle.net/10668/13232
UL http://hdl.handle.net/10668/13232
LA en
DS RISalud
RD Apr 7, 2025