RT Journal Article
T1 Sociodemographic, clinical and laboratory factors on admission associated with COVID-19 mortality in hospitalized patients: A retrospective observational study
A1 Rivera-Izquierdo, Mario
A1 Valero-Ubierna, María del Carmen
A1 R-delAmo, Juan Luis
A1 Fernández-García, Miguel Ángel
A1 Martínez-Diz, Silvia
A1 Tahery-Mahmoud, Arezu
A1 Rodríguez-Camacho, Marta
A1 Gámiz-Molina, Ana Belén
A1 Barba-Gyengo, Nicolás
A1 Gámez-Baeza, Pablo
A1 Cabrero-Rodríguez, Celia
A1 Guirado-Ruiz, Pedro Antonio
A1 Martín-Romero, Divina Tatiana
A1 Láinez-Ramos-Bossini, Antonio Jesús
A1 Sánchez-Pérez, María Rosa
A1 Mancera-Romero, José
A1 García-Martín, Miguel
A1 Martín-delosReyes, Luis Miguel
A1 Martínez-Ruiz, Virginia
A1 Lardelli-Claret, Pablo
A1 Jiménez-Mejías, Eladio
K1 Retrospective Studies
K1 COVID-19
K1 Coronavirus infections
K1 Risk factors
K1 Hospitalization
K1 Residence characteristics
K1 Demography
K1 Sociodemographic
K1 Spain
K1 Estudios retrospectivos
K1 Infecciones por coronavirus
K1 Factores de riesgo
K1 Hospitalización
K1 Características de la residencia
K1 Demografía
K1 España
K1 Andalucía
AB Background: To identify and quantify associations between baseline characteristics on hospital admission and mortality in patients with COVID-19 at a tertiary hospital in Spain.Methods and findings: This retrospective case series included 238 patients hospitalized for COVID-19 at Hospital Universitario Clínico San Cecilio (Granada, Spain) who were discharged or who died. Electronic medical records were reviewed to obtain information on sex, age, personal antecedents, clinical features, findings on physical examination, and laboratory results for each patient. Associations between mortality and baseline characteristics were estimated as hazard ratios (HR) calculated with Cox regression models. Series mortality was 25.6%. Among patients with dependence for basic activities of daily living, 78.7% died, and among patients residing in retirement homes, 80.8% died. The variables most clearly associated with a greater hazard of death were age (3% HR increase per 1-year increase in age; 95%CI 1-6), diabetes mellitus (HR 2.42, 95%CI 1.43-4.09), SatO2/FiO2 ratio (43% HR reduction per 1-point increase; 95%CI 23-57), SOFA score (19% HR increase per 1-point increase, 95%CI 5-34) and CURB-65 score (76% HR increase per 1-point increase, 95%CI 23-143).Conclusions: The patients residing in retirement homes showed great vulnerability. The main baseline factors that were independently associated with mortality in patients hospitalized for COVID-19 were older age, diabetes mellitus, low SatO2/FiO2 ratio, and high SOFA and CURB-65 scores.
PB Muhammad Adrish, BronxCare Health System, Affiliated with Icahn School of Medicine at Mount Sinai, United States. Commercial Publisher: Public Library of Science.
YR 2020
FD 2020-06-25
LK http://hdl.handle.net/10668/3286
UL http://hdl.handle.net/10668/3286
LA en
NO Rivera-Izquierdo M, del Carmen Valero-Ubierna M, R-delAmo JL, Fernández-García MÁ, Martínez-Diz S, Tahery-Mahmoud A, et al. Sociodemographic, clinical and laboratory factors on admission associated with COVID-19 mortality in hospitalized patients: A retrospective observational study. PLoS One. 2020 Jun 25;15(6):e0235107.
DS RISalud
RD Apr 17, 2025