TY - JOUR AU - Malmierca, Mónica G AU - Pérez-Victoria, Ignacio AU - Martín, Jesús AU - Reyes, Fernando AU - Méndez, Carmen AU - Olano, Carlos AU - Salas, José A PY - 2018 DO - 10.1128/AEM.01462-18 UR - http://hdl.handle.net/10668/12709 T2 - Applied and environmental microbiology AB - Macrolactams comprise a family of natural compounds with important bioactivities, such as antibiotic, antifungal, and antiproliferative activities. Sipanmycins A and B are two novel members of this family, with two sugar moieties attached to the... LA - en KW - Streptomyces KW - actinomycetes KW - antibiotics KW - biosynthesis gene cluster KW - glycosylation KW - glycosyltransferases KW - sugars KW - Amino Sugars KW - Bacterial Proteins KW - Biosynthetic Pathways KW - Cloning, Molecular KW - Glycosylation KW - Glycosyltransferases KW - Multigene Family KW - Polyketides KW - Streptomyces TI - Cooperative Involvement of Glycosyltransferases in the Transfer of Amino Sugars during the Biosynthesis of the Macrolactam Sipanmycin by Streptomyces sp. Strain CS149. TY - research article VL - 84 ER -