RT Journal Article
T1 Subclinical Arteriosclerosis is Associated With Common Vascular Risk Factors in Long-Term Survivors of Testicular Cancer.
A1 Espíldora-Hernández, Javier
A1 Díaz-Antonio, Tania
A1 Baena-Espinar, Javier
A1 Alonso-Calderón, Inmaculada
A1 Rioja, José
A1 Alba-Conejo, Emilio
A1 Valdivielso, Pedro
A1 Sánchez-Chaparro, Miguel-Ángel
K1 arterial ultrasound
K1 liver steatosis
K1 subclinical arteriosclerosis
K1 testicular cancer
K1 vascular calcification
AB Cardiovascular disease risk is increased in survivors of testicular cancer because of exposure to treatment (chemotherapy and radiotherapy), as well as modification in lifestyle. Our aim was to assess the presence of subclinical arteriosclerosis in survivors of testicular cancer in comparison with a control group. This was a cross-sectional, observational, case-control study including 50 survivors of Germ Cell Tumor (GCT) (14 years of follow-up) and 53 age-matched controls with no cancer. We registered clinical data, cardiovascular risk factors, physical and Mediterranean questionnaires, intima-media thickness and plaque at carotid and femoral arteries by ultrasound, calcium score at the abdominal aorta, and liver steatosis by computed tomography, and applied analytical tests to quantify metabolic risk factors and inflammation markers. Patients showed a trend toward greater intima-media thickness (IMT) and plaques than controls, as well as a higher calcium score in the abdominal aorta. Remarkably, patients had higher waist circumference, insulin resistance (HOMA-IR), and liver steatosis, but lower physical activity and high-density lipoprotein (HDL) cholesterol than controls (all p
SN 2077-0383
YR 2020
FD 2020-03-31
LK https://hdl.handle.net/10668/27072
UL https://hdl.handle.net/10668/27072
LA en
DS RISalud
RD Apr 5, 2025