TY - JOUR AU - Soret, Perrine AU - Le-Dantec, Christelle AU - Desvaux, Emiko AU - Foulquier, Nathan AU - Chassagnol, Bastien AU - Hubert, Sandra AU - Jamin, Christophe AU - Barturen, Guillermo AU - Desachy, Guillaume AU - Devauchelle-Pensec, Valerie AU - Boudjeniba, Cheïma AU - Cornec, Divi AU - Saraux, Alain AU - Jousse-Joulin, Sandrine AU - Barbarroja, Nuria AU - Rodriguez-Pinto, Ignasi AU - De Langhe, Ellen AU - Beretta, Lorenzo AU - Chizzolini, Carlo AU - Kovacs, Laszlo AU - Witte, Torsten AU - Bettacchioli, Eleonore AU - Buttgereit, Anne AU - Makowska, Zuzanna AU - Lesche, Ralf AU - Borghi, Maria Orietta AU - Martin, Javier AU - Courtade-Gaiani, Sophie AU - Xuereb, Laura AU - Guedj, Mickaël AU - Moingeon, Philippe AU - Alarcon-Riquelme, Marta E AU - Laigle, Laurence AU - Pers, Jacques-Olivier PY - 2021 DO - 10.1038/s41467-021-23472-7 UR - http://hdl.handle.net/10668/17985 T2 - Nature communications AB - There is currently no approved treatment for primary Sjögren's syndrome, a disease that primarily affects adult women. The difficulty in developing effective therapies is -in part- because of the heterogeneity in the clinical manifestation and... LA - en PB - Nature Publishing Group KW - Autoantibodies KW - Biomarkers KW - Chemokines KW - Cohort studies KW - Computational diology KW - Computer simulation KW - Adult KW - Cytokines KW - DNA methylation KW - Databases, genetic KW - Databases, protein KW - Female KW - Flow cytometry KW - Genome-wide association study KW - Humans KW - Inflammation KW - Interferons KW - Male KW - Middle aged KW - Multigene family KW - Polymorphism, single nucleotide KW - Proteome KW - RNA-seq KW - Sjogren's syndrome KW - Transcriptome TI - A new molecular classification to drive precision treatment strategies in primary Sjögren's syndrome. TY - research article VL - 12 ER -