RT Journal Article T1 Pseudochelin A, a siderophore of Pseudoalteromonas piscicida S2040 A1 Sonnenschein, Eva C. A1 Stierhof, Marc A1 Goralczyk, Stephan A1 Vabre, Floriane M. A1 Pellissier, Leonie A1 Hanssen, Kine Ostnes A1 de la Cruz, Mercedes A1 Diaz, Caridad A1 de Witte, Peter A1 Copmans, Danielle A1 Andersen, Jeanette Hammer A1 Hansen, Espen A1 Kristoffersen, Venke A1 Tormo, Jose R. A1 Ebel, Rainer A1 Milne, Bruce F. A1 Deng, Hai A1 Gram, Lone A1 Jaspars, Marcel A1 Tabudravu, Jioji N. K1 Pseudoalteromonas K1 Siderophore K1 Pseudochelin A K1 NMR K1 LCMS K1 Microbial iron transport K1 Coordination chemistry K1 Pseudomonas-aeruginosa K1 Vibrio-cholerae K1 Mycobacterium-tuberculosis K1 Siderocalin K1 Recognition K1 Acquisition K1 Pyochelin K1 Microorganisms AB A new siderophore containing a 4,5-dihydroimidazole moiety was isolated from Pseudoalteromonas piscicida S2040 together with myxochelins A and B, alteramide A and its cycloaddition product, and bromo- and dibromoalterochromides. The structure of pseudochelin A was established by spectroscopic techniques including 2D NMR and MS/MS fragmentation data. In bioassays selected fractions of the crude extract of S2040 inhibited the opportunistic pathogen Pseudomonas aeruginosa. Pseudochelin A displayed siderophore activity in the chrome azurol S assay at concentrations higher than 50 mu M, and showed weak activity against the fungus Aspergillus fumigatus, but did not display antibacterial, anti-inflammatory or anticonvulsant activity. (C) 2017 Elsevier Ltd. All rights reserved. PB Pergamon-elsevier science ltd SN 0040-4020 YR 2017 FD 2017-05-04 LK http://hdl.handle.net/10668/18888 UL http://hdl.handle.net/10668/18888 LA en DS RISalud RD Apr 11, 2025