TY - JOUR AU - Calderón-Sánchez, Eva AU - Díaz, Ignacio AU - Ordóñez, Antonio AU - Smani, Tarik PY - 2016 DO - 10.1371/journal.pone.0147375 UR - http://hdl.handle.net/10668/9807 T2 - PloS one AB - Urocortin-1 (Ucn-1) is an endogenous peptide that protects heart from ischemia and reperfusion (I/R) injuries. Ucn-1 is known to prevent cardiac cell death, but its role in the transcription of specific genes related to survival signaling pathway has... LA - en KW - Animals KW - Apoptosis KW - CD40 Ligand KW - Cardiotonic Agents KW - Caspases KW - Cell Survival KW - Disease Models, Animal KW - Gene Expression Regulation KW - Guanine Nucleotide Exchange Factors KW - Hemodynamics KW - Male KW - Mitogen-Activated Protein Kinase 1 KW - Mitogen-Activated Protein Kinase 3 KW - Myocardial Contraction KW - Myocardial Reperfusion Injury KW - Myocardium KW - Myocytes, Cardiac KW - Phosphorylation KW - Rats KW - Signal Transduction KW - Urocortins KW - X-Linked Inhibitor of Apoptosis Protein TI - Urocortin-1 Mediated Cardioprotection Involves XIAP and CD40-Ligand Recovery: Role of EPAC2 and ERK1/2. TY - research article VL - 11 ER -