RT Journal Article T1 Underlying heart diseases and acute COVID-19 outcomes. A1 Núñez-Gil, Iván J A1 Fernández-Ortiz, Antonio A1 Maroud Eid, Charbel A1 Huang, Jia A1 Romero, Rodolfo A1 Becerra-Muñoz, Victor Manuel A1 Uribarri, Aitor A1 Feltes, Gisela A1 Trabatoni, Daniela A1 Fernandez-Rozas, Inmaculada A1 Viana-Llamas, Maria C A1 Pepe, Martino A1 Cerrato, Enrico A1 Bertaina, Maurizio A1 Capel Astrua, Thamar A1 Alfonso, Emilio A1 Castro-Mejía, Alex F A1 Raposeiras-Roubin, Sergio A1 D'Ascenzo, Fabrizio A1 Espejo Paeres, Carolina A1 Signes-Costa, Jaime A1 Bardaji, Alfredo A1 Fernandez-Pérez, Cristina A1 Marin, Francisco A1 Fabregat-Andres, Oscar A1 Akin, Ibrahim A1 Estrada, Vicente A1 Macaya, Carlos K1 COVID-19 K1 cardiology K1 heart disease K1 mortality K1 prognosis K1 registry AB The presence of any underlying heart condition could influence outcomes during the coronavirus disease 2019 (COVID-19). The registry HOPE-COVID-19 (Health Outcome Predictive Evaluation for COVID-19, NCT04334291) is an international ambispective study, enrolling COVID-19 patients discharged from hospital, dead or alive. HOPE enrolled 2798 patients from 35 centers in 7 countries. Median age was 67 years (IQR: 53.0-78.0), and most were male (59.5%). A relevant heart disease was present in 682 (24%) cases. These were older, more frequently male, with higher overall burden of cardiovascular risk factors (hypertension, dyslipidemia, diabetes mellitus, smoking habit, obesity) and other comorbidities such renal failure, lung, cerebrovascular disease and oncologic antecedents (p An underlying heart disease is an adverse prognostic factor for patients suffering COVID-19. Its presence could be related with different clinical drug management and would benefit from maintaining treatment with angiotensin converting enzyme inhibitors or angiotensin receptor blockers during in-hospital stay. YR 2020 FD 2020-12-21 LK http://hdl.handle.net/10668/16827 UL http://hdl.handle.net/10668/16827 LA en DS RISalud RD Apr 10, 2025