TY  - JOUR
AU  - Garcia-Leon, Juan Antonio
AU  - Vitorica, Javier
AU  - Gutierrez, Antonia
PY  - 2019
DO  - 10.4155/fmc-2018-0520
UR  - http://hdl.handle.net/10668/14074
T2  - Future medicinal chemistry
AB  - Most neurodegenerative diseases are characterized by a complex and mostly still unresolved pathology. This fact, together with the lack of reliable disease models, has precluded the development of effective therapies counteracting the disease...
LA  - en
KW  - Alzheimer’s disease
KW  - CRISPR-Cas9
KW  - Huntington’s disease
KW  - Parkinson’s disease
KW  - amyotrophic lateral sclerosis
KW  - disease modeling
KW  - drug screening
KW  - hiPSCs
KW  - human-induced pluripotent stem cells
KW  - multiple sclerosis
KW  - neurodegenerative disease
KW  - Animals
KW  - CRISPR-Cas Systems
KW  - Drug Evaluation, Preclinical
KW  - Gene Editing
KW  - Humans
KW  - Neurodegenerative Diseases
KW  - Neurogenesis
KW  - Neurons
KW  - Pluripotent Stem Cells
TI  - Use of human pluripotent stem cell-derived cells for neurodegenerative disease modeling and drug screening platform.
TY  - research article
VL  - 11
ER  -