RT Journal Article T1 Concurrent validity of supraclavicular skin temperature measured with iButtons and infrared thermography as a surrogate marker of brown adipose tissue. A1 Martinez-Tellez, Borja A1 Perez-Bey, Alejandro A1 Sanchez-Delgado, Guillermo A1 Acosta, Francisco M A1 Corral-Perez, Juan A1 Amaro-Gahete, Francisco J A1 Alcantara, Juan M A A1 Castro-Piñero, Jose A1 Jimenez-Pavon, David A1 Llamas-Elvira, Jose M A1 Ruiz, Jonatan R K1 Skin temperature K1 Thermoregulation K1 brown fat AB Brown adipose tissue (BAT) thermogenic activity is commonly assessed with a positron emission tomography with computed tomography scan (PET/CT). This technique has several limitations and alternative techniques are needed. Supraclavicular skin temperature measured with iButtons and infrared thermography (IRT) has been proposed as an indirect marker of BAT activity. We studied the concurrent validity of skin temperature measured with iButtons vs. IRT and the association of supraclavicular skin temperature measured with iButtons and IRT with BAT. We measured skin temperature upon a shivering threshold test with iButtons and IRT in 6 different regions in 12 participants (n = 2 men). On a separate day, we determined supraclavicular skin temperature with an iButton and IRT after 2 h of a personalized cooling protocol. Thereafter, we quantified BAT volume and activity by PET/CT. We observed that the absolute differences between the devices were statistically different from 0 (all P  PB Elsevier Ltd SN 0306-4565 YR 2019 FD 2019-04-15 LK http://hdl.handle.net/10668/14020 UL http://hdl.handle.net/10668/14020 LA en NO Martinez-Tellez B, Perez-Bey A, Sanchez-Delgado G, Acosta FM, Corral-Perez J, Amaro-Gahete FJ, et al. Concurrent validity of supraclavicular skin temperature measured with iButtons and infrared thermography as a surrogate marker of brown adipose tissue. J Therm Biol. 2019 May;82:186-196. NO We are grateful to Ms. Carmen Sainz-Quinn for assistance with the English language. We are grateful to Alberto Quesada-Aranda for helping with the development of the Temperatus software (Free trial inttp://profth.ugr.es/temperatus ). This study was supported by the Spanish Ministry of Economy and Competitiveness via the Fondo de Investigación Sanitaria del Instituto de Salud Carlos III ( PI13/01393), Retos de la sociedad (DEP2016-79512-R), PTA 12264-I, and European Regional Development Fund (ERDF), the Spanish Ministry of Education (FPU 13/04365, FPU14/04172, FPU15/05337, and FPU15/04059), by the Spanish Ministry of Science and Innovation-MINECO (RYC-2014-16938), the Fundación Iberoamericana de Nutrición (FINUT), the Redes Temáticas de Investigación Cooperativa RETIC (Red SAMID RD16/0022), the AstraZeneca HealthCare Foundation, the University of Granada Plan Propio de Investigación 2016 -Excellence actions: Unit of Excellence on Exercise and Health (UCEES) - and Plan Propio de Investigación 2018 - Programa Contratos-Puente, and the Junta de Andalucía, Consejería de Conocimiento, Investigación y Universidades (ERDF, ref. SOMM17/6107/UGR). This study is part of a Ph.D. Thesis conducted in the Biomedicine Doctoral Studies of the University of Granada, Spain. DS RISalud RD Apr 7, 2025