RT Journal Article T1 Quality of life in patients with breakthrough cancer pain in radiation oncology departments in Spain: the CAVIDIOR study. A1 Hernanz de Lucas, Raúl A1 Nuñez Fernández, Míriam A1 Gómez-Caamaño, Antonio A1 Morera López, Rosa A1 Fortes de la Torre, Inmaculada A1 de la Torre Tomás, Alejandro A1 Muñoz-Garzón, Víctor A1 López Bermudo, Cristina A1 Mañas Rueda, Ana K1 breakthrough cancer pain K1 palliative care K1 quality of life K1 radiation oncology K1 transmucosal fentanyl AB Aim: The CAVIDIOR study evaluated quality of life (QoL) in patients with breakthrough cancer pain receiving palliative radiation therapy in radiation oncology departments (RODs) in Spain. Patients & methods: Prospective observational study at 11 Spanish RODs (July 2016-November 2017). QoL was assessed using Short Form Health Survey 12. Secondary end points were sleep quality, caregiver burden and patient/perception of improvement. Results: QoL improved according to the Short Form Health Survey 12 mental component. Sleep quality and caregivers' burden improved significantly. Conclusion: Breakthrough cancer pain is highly prevalent and can be substantially reduced with appropriate diagnosis and management in RODs. Along with the QoL questionnaire, sleep quality and caregiver burden provide a more comprehensive assessment of overall health status in patients receiving radiation therapy in RODs. Clinical trial registration: NCT02836379 (ClinicalTrials.gov). YR 2020 FD 2020-12-08 LK http://hdl.handle.net/10668/16753 UL http://hdl.handle.net/10668/16753 LA en DS RISalud RD Apr 19, 2025