TY - JOUR AU - Jimenez-Guerrero, Rocio AU - Gasca, Jessica AU - Flores, M Luz AU - Perez-Valderrama, BegoƱa AU - Tejera-Parrado, Cristina AU - Medina, Rafael AU - Tortolero, Maria AU - Romero, Francisco AU - Japon, Miguel A AU - Saez, Carmen PY - 2018 DO - 10.3390/cancers10120490 SN - 2072-6694 UR - http://hdl.handle.net/10668/13326 T2 - Cancers AB - Paclitaxel is a treatment option for advanced or metastatic bladder cancer after the failure of first-line cisplatin and gemcitabine, although resistance limits its clinical benefits. Mcl-1 is an anti-apoptotic protein that promotes resistance to... LA - en PB - MDPI AG KW - apoptosis KW - autophagy KW - bladder cancer KW - obatoclax KW - paclitaxel KW - Gemcitabine KW - Cisplatin KW - Beclin-1 KW - Caspases KW - Apoptosis Regulatory Proteins KW - Paclitaxel KW - Urinary Bladder Neoplasms KW - Autophagy KW - Blotting, Western KW - Carcinoma TI - Obatoclax and Paclitaxel Synergistically Induce Apoptosis and Overcome Paclitaxel Resistance in Urothelial Cancer Cells. TY - research article VL - 10 ER -