TY - JOUR AU - Rodríguez-Gómez, José A. AU - Kavanagh, Edel AU - Engskog-Vlachos, Pinelopi AU - Engskog, Mikael K. R. AU - Herrera, Antonio J. AU - Espinosa-Oliva, Ana M. AU - Joseph, Bertrand AU - Hajji, Nabil AU - Venero, José L. AU - Burguillos, Miguel A. PY - 2020 DO - 10.3390/cells9071717 UR - http://hdl.handle.net/10668/3592 T2 - Cells AB - The pro-inflammatory immune response driven by microglia is a key contributor to the pathogenesis of several neurodegenerative diseases. Though the research of microglia spans over a century, the last two decades have increased our understanding... LA - en PB - MDPI KW - Microglia KW - Inflammation KW - TLR4 KW - TREM2 KW - Caspases KW - Epigenetics KW - metabolomics KW - iPSCs KW - Microglía KW - Inflamación KW - Receptor Toll-Like 4 KW - Caspasas KW - Epigenómica KW - Metabolómica KW - Células madre pluripotentes inducidas KW - Medical Subject Headings::Organisms::Eukaryota::Animals KW - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Peptides::Intracellular Signaling Peptides and Proteins::Apoptosis Regulatory Proteins::Caspases KW - Medical Subject Headings::Anatomy::Nervous System::Central Nervous System KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Processes::Gene Expression Regulation::Epigenesis, Genetic KW - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans KW - Medical Subject Headings::Diseases::Pathological Conditions, Signs and Symptoms::Pathologic Processes::Inflammation KW - Medical Subject Headings::Anatomy::Cells::Neuroglia::Microglia KW - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Models, Theoretical::Models, Biological KW - Medical Subject Headings::Anatomy::Cells::Stem Cells::Pluripotent Stem Cells::Induced Pluripotent Stem Cells KW - Medical Subject Headings::Disciplines and Occupations::Natural Science Disciplines::Biological Science Disciplines::Biology::Genetics::Genomics::Epigenomics TI - Microglia: Agents of the CNS Pro-Inflammatory Response TY - review article ER -