RT Journal Article T1 Evaluation of Gonadal Alterations in a Population Environmentally Exposed to a Mixture of Endocrine Active Pesticides. A1 Requena-Mullor, Mar A1 Navarro-Mena, Angeles A1 Wei, Ruqiong A1 López-Guarnido, Olga A1 Lozano-Paniagua, David A1 Alarcon-Rodriguez, Raquel K1 endocrine disruption K1 gonadal dysfunction K1 ovarian cancer K1 pesticide K1 testicular cancer AB Although there are studies that show that some pesticides produce gonadal dysfunction and gonadal cancer in different animals, there are not many studiesregardinghumans. This study determined the prevalence and risk in humans of developing ovarian or testicular dysfunction or cancer in areas with distinct exposure to pesticides, which have endocrine disrupting properties. A population-based case-control study was carried out on humans living in ten health districts of Andalusia (Southern Spain) classified as areas of high or low environmental exposure to pesticides according to agronomic criteria. The study population included 5332 cases and 13,606 controls. Data were collected from computerized hospital records between 2000 and 2018.The risk of gonadal dysfunction or cancer was significantly higher in areas with higher use of pesticides in relation to those with lower use. YR 2021 FD 2021-02-28 LK http://hdl.handle.net/10668/17290 UL http://hdl.handle.net/10668/17290 LA en DS RISalud RD Apr 17, 2025