TY - JOUR AU - Fernandez-Fernandez, Seila AU - Bobo-Jimenez, Veronica AU - Requejo-Aguilar, Raquel AU - Gonzalez-Fernandez, Silvia AU - Resch, Monica AU - Carabias-Carrasco, Monica AU - Ros, Joaquim AU - Almeida, Angeles AU - BolaƱos, Juan P PY - 2018 DO - 10.1016/j.redox.2018.08.003 UR - http://hdl.handle.net/10668/12834 T2 - Redox biology AB - Loss of brain glutathione has been associated with cognitive decline and neuronal death during aging and neurodegenerative diseases. However, whether decreased glutathione precedes or follows neuronal dysfunction has not been unambiguously elucidated.... LA - en PB - Elsevier KW - Dendrite disruption KW - Glutamate-cysteine ligase KW - Glutathione KW - In vivo knockdown KW - Memory impairment KW - Neurons KW - Animals KW - Cognition KW - Dendrites KW - Glutathione KW - Hippocampus KW - Male KW - Mice, inbred C57BL KW - Neurons KW - Oxidation-reduction KW - Oxidative stress TI - Hippocampal neurons require a large pool of glutathione to sustain dendrite integrity and cognitive function. TY - research article VL - 19 ER -