RT Journal Article
T1 Fendrix(R) Vaccine Effectiveness in Healthcare Workers Who Are Non-Responsive to Engerix B(R) Vaccination
A1 Jose Tejada-Perez, Juan
A1 Jose Vazquez-Vicente, Juan
A1 Renee Herrera-Burgos, Maria
A1 Gabriel Martin-Martin, Francisco
A1 Parron-Carreno, Tesifon
A1 Alarcon-Rodriguez, Raquel
K1 Hepatitis B
K1 vaccination
K1 fendrix
K1 healthcare workers
K1 occupational health
K1 Hepatitis-b-vaccine
AB Hepatitis B (HBV) is a pathogen virus with transmission mechanisms that include contact with the infected blood or bodily fluids of the infected organism. Nowadays, healthcare workers are one of the most exposed groups to HBV. Conventionally, completing a vaccine series dosage with Engerix B(R) lowers this risk by providing workers with immunity to the virus. However, through the years, we have encountered nonresponsive health personnel to the Engerix B(R) vaccine; hence, the Occupational Health Service of Poniente Hospital studied the Fendrix(R) adjuvanted vaccine as an alternative vaccine to develop immunological responses in healthcare workers who do not respond to vaccination with Engerix B(R). In our study, we employed a vaccination schedule with the Fendrix(R) vaccine, performing serology tests on the cases after the application of each dose. The results obtained showed humoral immunity in 92.3% of the cases, with a remarkable increase in antibody titer after the first doses. These encouraging results support the future inclusion of this vaccine as one possible alternative for the immunization to HBV for healthcare workers nonresponsive to Engerix B(R).
PB Mdpi
YR 2021
FD 2021-03-01
LK http://hdl.handle.net/10668/19334
UL http://hdl.handle.net/10668/19334
LA en
DS RISalud
RD Apr 18, 2025