RT Journal Article T1 Influence of the Covid-19 pandemic on out-of-hospital cardiac arrest. A Spanish nationwide prospective cohort study. A1 Rosell Ortiz, Fernando A1 Fernández Del Valle, Patricia A1 Knox, Emily C A1 Jiménez Fábrega, Xavier A1 Navalpotro Pascual, José M A1 Mateo Rodríguez, Inmaculada A1 Ruiz Azpiazu, José I A1 Iglesias Vázquez, José A A1 Echarri Sucunza, Alfredo A1 Alonso Moreno, Daniel F A1 Forner Canos, Ana B A1 García-Ochoa Blanco, María J A1 López Cabeza, Nuria A1 Mainar Gómez, Belén A1 Batres Gómez, Susana A1 Cortés Ramas, José A A1 Ceniceros Rozalén, María I A1 Guirao Salas, Francisco A A1 Fernández Martínez, Begoña A1 Daponte Codina, Antonio A1 OHSCAR investigators, K1 Covid 19 K1 Emergency services K1 Out-of hospital cardiac arrest K1 Survival AB The influence of the COVID-19 pandemic on attendance to out-of-hospital cardiac arrest (OHCA) has only been described in city or regional settings. The impact of COVID-19 across an entire country with a high infection rate is yet to be explored. The study uses data from 8629 cases recorded in two time-series (2017/2018 and 2020) of the Spanish national registry. Data from a non-COVID-19 period and the COVID-19 period (February 1st-April 30th 2020) were compared. During the COVID-19 period, data a further analysis comparing non-pandemic and pandemic weeks (defined according to the WHO declaration on March 11th, 2020) was conducted. The chi-squared analysis examined differences in OHCA attendance and other patient and resuscitation characteristics. Multivariate logistic regression examined survival likelihood to hospital admission and discharge. The multilevel analysis examined the differential effects of regional COVID-19 incidence on these same outcomes. During the COVID-19 period, the incidence of resuscitation attempts declined and survival to hospital admission (OR = 1.72; 95%CI = 1.46-2.04; p  The pandemic, irrespective of its incidence, seems to have particularly impeded the pre-hospital phase of OHCA care. Present findings call for the need to adapt out-of-hospital care for periods of serious infection risk. ISRCTN10437835. YR 2020 FD 2020-10-10 LK https://hdl.handle.net/10668/27260 UL https://hdl.handle.net/10668/27260 LA en DS RISalud RD Apr 4, 2025