RT Journal Article
T1 Ultrasound-assisted intralesional corticosteroid infiltrations for patients with hidradenitis suppurativa
A1 Salvador-Rodríguez, Luis
A1 Arias-Santiago, Salvador
A1 Molina-Leyva, Alejandro
K1 Abscess
K1 Adrenal cortex hormones
K1 Cohort studies
K1 Hidradenitis suppurativa
K1 Fistula
K1 Patients
K1 Triamcinolone acetonide
K1 Ultrasonography, interventional
K1 Absceso
K1 Corticoesteroides
K1 Estudios de cohortes
K1 Hidradenitis supurativa
K1 Fístula
K1 Pacientes
K1 Triamcinolona acetonida
K1 Ultrasonografía intervencional
AB Corticosteroid infiltrations of lesions in hidradenitis suppurativa (HS) appear to be beneficial to acute flares. The aim of this study is to evaluate the effectiveness and safety of ultrasound-assisted intralesional corticosteroid infiltrations to HS lesions. Prospective cohort study between February 2017 and February 2019 on patients with mild to severe HS and one or more inflammatory lesions. The study intervention was ultrasound-assisted intralesional infiltration of triamcinolone acetonide 40 mg/ml. The main outcome was the complete response rate of infiltrated lesions versus non-infiltrated lesions. Two hundred and forty-seven infiltrated inflammatory lesions and 172 non-infiltrated lesions were included. At week 12, 81.1% (30/37) of nodules, 72.0% (108/150) of abscesses and 53.33% (32/60) of draining fistulas presented complete response versus 69.1% (47/68), 54.3% (38/70) and 35.3% (12/34) respectively for the non-infiltrated lesions. The Hurley stage negatively correlated with complete response for abscesses and draining fistulas at - 0.17 (SD 0.06) p < 0.01 and - 0.30 (SD 0.13) p < 0.02 respectively. Ultrasound-assisted corticosteroid infiltration is a useful technique for the treatment of inflammatory HS lesions, with high and sustained response rates, especially for abscesses and small to medium-size simple draining fistulas. The likelihood of response correlates negatively with the Hurley stage.
PB Springer Nature
YR 2020
FD 2020-08-07
LK http://hdl.handle.net/10668/3555
UL http://hdl.handle.net/10668/3555
LA en
NO Salvador-Rodríguez L, Arias-Santiago S, Molina-Leyva A. Ultrasound-assisted intralesional corticosteroid infiltrations for patients with hidradenitis suppurativa. Sci Rep. 2020 Aug 7;10(1):13363
DS RISalud
RD Apr 7, 2025