TY - JOUR AU - Sakellariou, Despoina AU - Bak, Sara Thornby AU - Isik, Esin AU - Barroso, Sonia I AU - Porro, Antonio AU - Aguilera, Andrés AU - Bartek, Jiri AU - Janscak, Pavel AU - Peña-Diaz, Javier PY - 2022 DO - 10.1016/j.celrep.2022.110602 UR - http://hdl.handle.net/10668/22075 T2 - Cell reports AB - Up to 15% of human cancers maintain their telomeres through a telomerase-independent mechanism, termed "alternative lengthening of telomeres" (ALT) that relies on homologous recombination between telomeric sequences. Emerging evidence suggests that... LA - en KW - ALT cancers KW - C-circle KW - CP: Cancer KW - CP: Molecular biology KW - G-quadruplex KW - R-loop KW - mismatch repair KW - telomere KW - DNA KW - Humans KW - Neoplasms KW - R-Loop Structures KW - RNA, Long Noncoding KW - Telomere KW - Telomere Homeostasis TI - MutSβ regulates G4-associated telomeric R-loops to maintain telomere integrity in ALT cancer cells. TY - research article VL - 39 ER -