TY - JOUR AU - Carola, G AU - Malagarriga, D AU - Calatayud, C AU - Pons-Espinal, M AU - Blasco-Agell, L AU - Richaud-Patin, Y AU - Fernandez-Carasa, I AU - Baruffi, V AU - Beltramone, S AU - Molina, E AU - Dell'Era, P AU - Toledo-Aral, J J AU - Tolosa, E AU - Muotri, A R AU - Garcia Ojalvo, J AU - Soriano, J AU - Raya, A AU - Consiglio, A PY - 2021 DO - 10.1038/s41531-021-00198-3 SN - 2373-8057 UR - https://hdl.handle.net/10668/27864 T2 - NPJ Parkinson's disease AB - A deeper understanding of early disease mechanisms occurring in Parkinson's disease (PD) is needed to reveal restorative targets. Here we report that human induced pluripotent stem cell (iPSC)-derived dopaminergic neurons (DAn) obtained from healthy... LA - en TI - Parkinson's disease patient-specific neuronal networks carrying the LRRK2 G2019S mutation unveil early functional alterations that predate neurodegeneration. TY - research article VL - 7 ER -