%0 Journal Article %A Gonzalez-Cantero, Alvaro %A Teklu, Meron %A Sorokin, Alexander V %A Prussick, Ronald %A González-Cantero, Jorge %A Martin-Rodriguez, Jose Luis %A Patel, Nidhi %A Parel, Philip M %A Manyak, Grigory A %A Teague, Heather L %A Rodante, Justin A %A Keel, Andrew %A Pérez-Hortet, Cristina %A Sanchéz-Moya, Ana I %A Jiménez, Natalia %A Ballester, Asunción %A Solis, Jorge %A Fernandez-Friera, Leticia %A Barderas, María G %A Gonzalez-Calvin, Jorge L %A Jaen, Pedro %A Playford, Martin P %A Dey, Amit K %A Gelfand, Joel M %A Mehta, Nehal N %T Subclinical Liver Disease Is Associated with Subclinical Atherosclerosis in Psoriasis: Results from Two Observational Studies. %D 2021 %U http://hdl.handle.net/10668/22319 %X Psoriasis is associated with a higher risk of liver diseases. We investigated the impact of hepatic steatosis (European cohort) and hepatic inflammation (United States cohort) on subclinical atherosclerosis. In the European cohort (n = 76 psoriasis participants and 76 controls), nonalcoholic fatty liver disease, assessed by the sonographic hepatorenal index, was more prevalent in psoriasis than in controls (61% vs. 45%; P = 0.04). Participants with psoriasis with nonalcoholic fatty liver disease had a higher prevalence of subclinical atherosclerosis (ultrasonographic presence of plaque in femoral or carotid arteries) than participants with psoriasis without nonalcoholic fatty liver disease (61% vs. 23%; P = 0.006) and controls with nonalcoholic fatty liver disease (61% vs. 32%; P %~