RT Journal Article
T1 Evolution of Metabolic Phenotypes of Obesity in Coronary Patients after 5 Years of Dietary Intervention: From the CORDIOPREV Study
A1 Martin-Piedra, Laura
A1 Alcala-Diaz, Juan F.
A1 Gutierrez-Mariscal, Francisco M.
A1 Arenas de Larriva, Antonio P.
A1 Romero-Cabrera, Juan L.
A1 Torres-Pena, Jose D.
A1 Caballero-Villarraso, Javier
A1 Luque, Raul M.
A1 Perez-Martinez, Pablo
A1 Lopez-Miranda, Jose
A1 Delgado-Lista, Javier
K1 obesity metabolic phenotypes
K1 metabolically healthy obese
K1 metabolically unhealthy obese
K1 fatty liver index
K1 diet intervention
K1 Mediterranean diet
K1 low-fat diet
K1 coronary patients
K1 Body-fat distribution
K1 Healthy obesity
K1 Adipose-tissue
K1 Cardiovascular-disease
K1 European-society
K1 Task-force
K1 Inflammation
K1 Association
K1 Prevention
K1 Mass
AB Background: Obesity phenotypes with different metabolic status have been described previously. We analyzed metabolic phenotypes in obese coronary patients during a 5-year follow-up, and examined the factors influencing this evolution. Methods: The CORDIOPREV study is a randomized, long-term secondary prevention study with two healthy diets: Mediterranean and low-fat. All obese patients were classified as either metabolically healthy obese (MHO) or metabolically unhealthy obese (MUO). We evaluated the changes in the metabolic phenotypes and related variables after 5 years of dietary intervention. Results: Initially, 562 out of the 1002 CORDIOPREV patients were obese. After 5 years, 476 obese patients maintained their clinical and dietary visits; 71.8% of MHO patients changed to unhealthy phenotypes (MHO-Progressors), whereas the MHO patients who maintained healthy phenotypes (MHO-Non-Progressors) lost more in terms of their body mass index (BMI) and had a lower fatty liver index (FLI-score) (p
PB Mdpi
YR 2021
FD 2021-11-01
LK https://hdl.handle.net/10668/25863
UL https://hdl.handle.net/10668/25863
LA en
DS RISalud
RD Apr 11, 2025