TY - JOUR AU - Alonso-Alonso, Ruth AU - Mondéjar, Rufino AU - Martínez, Nerea AU - García-Diaz, Nuria AU - Pérez, Cristina AU - Merino, David AU - Rodríguez, Marta AU - Esteve-Codina, Anna AU - Fuste, Berta AU - Gut, Marta AU - Burrows, Francis AU - Scholz, Catherine AU - Vaqué, Jose Pedro AU - Gualberto, Antonio AU - Piris, Miguel Ángel PY - 2020 DO - 10.1038/s41598-020-63434-5 UR - http://hdl.handle.net/10668/15408 T2 - Scientific reports AB - Patients diagnosed with T-cell leukemias and T-cell lymphomas (TCLs) still have a poor prognosis and an inadequate response to current therapies, highlighting the need for targeted treatments. We have analyzed the potential therapeutic value of the... LA - en KW - Apoptosis KW - Biomarkers, Tumor KW - Cell Cycle KW - Cell Line, Tumor KW - Cell Survival KW - Down-Regulation KW - Drug Resistance, Neoplasm KW - Gene Expression Regulation, Leukemic KW - Humans KW - Inhibitory Concentration 50 KW - Lymphoma, T-Cell KW - Mutation KW - Phenotype KW - Precursor T-Cell Lymphoblastic Leukemia-Lymphoma KW - Quinolones KW - Signal Transduction KW - T-Lymphocytes TI - Identification of tipifarnib sensitivity biomarkers in T-cell acute lymphoblastic leukemia and T-cell lymphoma. TY - research article VL - 10 ER -