TY - JOUR AU - Cénit, María Carmen AU - Márquez, Ana AU - Cordero-Coma, Miguel AU - Fonollosa, Alejandro AU - Adán, Alfredo AU - Martínez-Berriotxoa, Agustín AU - Llorenç, Victor AU - Díaz Valle, David AU - Blanco, Ricardo AU - Cañal, Joaquín AU - Díaz-Llopis, Manuel AU - García Serrano, José Luis AU - Ramón, Enrique, de AU - Rio, María José, del AU - Gorroño-Echebarría, Marina AU - Martín-Villa, José Manuel AU - Ortego-Centeno, Norberto AU - Martín, Javier PY - 2013 DO - 10.1186/1471-2350-14-52 UR - http://hdl.handle.net/10668/1946 T2 - BMC medical genetics AB - BACKGROUNDRecently, different genetic variants located within the IL2/IL21 genetic region as well as within both IL2RA and IL2RB loci have been associated to multiple autoimmune disorders. We aimed to investigate for the first time the potential... LA - en PB - BioMed Central KW - IL2 KW - IL21 KW - IL2RA KW - Polymorphisms KW - Association study KW - Genetic susceptibility KW - Predisposición genética a la enfermedad KW - Variación genética KW - Genotipo KW - Interleucina-2 KW - Subunidad alfa del receptor de interleucina-2 KW - Polymorphism, Genetic KW - Modelos estadísticos KW - Polimorfismo de nucleótido simple KW - Uveítis KW - Medical Subject Headings::Named Groups::Persons::Age Groups::Adult::Aged KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Structures::Genome::Genome Components::Genes::Alleles KW - Medical Subject Headings::Health Care::Health Care Quality, Access, and Evaluation::Quality of Health Care::Health Care Evaluation Mechanisms::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Case-Control Studies KW - Medical Subject Headings::Check Tags::Female KW - Medical Subject Headings::Diseases::Pathological Conditions, Signs and Symptoms::Pathologic Processes::Disease Attributes::Disease Susceptibility::Genetic Predisposition to Disease KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Variation KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genotype KW - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans KW - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Peptides::Intercellular Signaling Peptides and Proteins::Cytokines::Interleukins::Interleukin-2 KW - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Membrane Proteins::Receptors, Cell Surface::Receptors, Immunologic::Receptors, Cytokine::Receptors, Interleukin::Receptors, Interleukin-2::Interleukin-2... KW - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Membrane Proteins::Receptors, Cell Surface::Receptors, Immunologic::Receptors, Cytokine::Receptors, Interleukin::Receptors, Interleukin-2::Interleukin-2... KW - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Peptides::Intercellular Signaling Peptides and Proteins::Cytokines::Interleukins KW - Medical Subject Headings::Check Tags::Male KW - Medical Subject Headings::Named Groups::Persons::Age Groups::Adult::Middle Aged KW - Medical Subject Headings::Health Care::Health Care Quality, Access, and Evaluation::Quality of Health Care::Health Care Evaluation Mechanisms::Statistics as Topic::Models, Statistical KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Variation::Polymorphism, Genetic KW - Polymorphism, Single Nucleotide KW - Medical Subject Headings::Diseases::Eye Diseases::Uveal Diseases::Uveitis KW - Medical Subject Headings::Named Groups::Persons::Age Groups::Adult TI - Evaluation of the IL2/IL21, IL2RA and IL2RB genetic variants influence on the endogenous non-anterior uveitis genetic predisposition. TY - research article ER -