TY - JOUR AU - Lucena-Cacace, Antonio AU - Otero-Albiol, Daniel AU - Jimenez-Garcia, Manuel P AU - Muñoz-Galvan, Sandra AU - Carnero, Amancio PY - 2017 DO - 10.1158/1078-0432.CCR-17-2575 UR - http://hdl.handle.net/10668/11872 T2 - Clinical cancer research : an official journal of the American Association for Cancer Research AB - Purpose: Colorectal cancer is the second most common cancer in women and the third most common in men worldwide. However, despite current progress, many patients with advanced and metastatic tumors still die from the malignancy. Refractory disease... LA - en PB - American Association for Cancer Research KW - Colonic Neoplasms KW - Drug Resistance, Neoplasm KW - Humans KW - Oncogenes KW - Prognosis KW - Sirtuin 1 KW - Xenograft Model Antitumor Assays KW - Animals KW - Cell Line, Tumor KW - Colon KW - Cytokines KW - Datasets as Topic KW - Female KW - Gene Expression Profiling KW - Mice, Nude KW - NAD KW - Neoplastic Stem Cells KW - Nicotinamide Phosphoribosyltransferase KW - Poly (ADP-Ribose) Polymerase-1 KW - RNA, Small Interfering KW - Signal Transduction KW - Survival Analysis TI - NAMPT Is a Potent Oncogene in Colon Cancer Progression that Modulates Cancer Stem Cell Properties and Resistance to Therapy through Sirt1 and PARP. TY - research article VL - 24 ER -