RT Journal Article
T1 Standardized Map of Iodine Status in Europe.
A1 Ittermann, Till
A1 Albrecht, Diana
A1 Arohonka, Petra
A1 Bilek, Radovan
A1 de Castro, Joao J
A1 Dahl, Lisbeth
A1 Filipsson Nystrom, Helena
A1 Gaberscek, Simona
A1 Garcia-Fuentes, Eduardo
A1 Gheorghiu, Monica L
A1 Hubalewska-Dydejczyk, Alicja
A1 Hunziker, Sandra
A1 Jukic, Tomislav
A1 Karanfilski, Borislav
A1 Koskinen, Seppo
A1 Kusic, Zvonko
A1 Majstorov, Venjamin
A1 Makris, Konstantinos C
A1 Markou, Kostas B
A1 Meisinger, Christa
A1 Milevska Kostova, Neda
A1 Mullen, Karen R
A1 Nagy, Endre V
A1 Pirags, Valdis
A1 Rojo-Martinez, Gemma
A1 Samardzic, Mira
A1 Saranac, Ljiljana
A1 Strele, Ieva
A1 Thamm, Michael
A1 Top, Işık
A1 Trofimiuk-Müldner, Malgorzata
A1 Ünal, Belgin
A1 Koskinen, Seppo
A1 Vila, Lluis
A1 Vitti, Paolo
A1 Winter, Benjamin
A1 Woodside, Jayne V
A1 Zaletel, Katja
A1 Zamrazil, Vaclav
A1 Zimmermann, Michael
A1 Erlund, Iris
A1 Völzke, Henry
K1 epidemiology
K1 iodine
K1 iodine supply
K1 method comparison
AB Background: Knowledge about the population's iodine status is important, because it allows adjustment of iodine supply and prevention of iodine deficiency. The validity and comparability of iodine-related population studies can be improved by standardization, which was one of the goals of the EUthyroid project. The aim of this study was to establish the first standardized map of iodine status in Europe by using standardized urinary iodine concentration (UIC) data. Materials and Methods: We established a gold-standard laboratory in Helsinki measuring UIC by inductively coupled plasma mass spectrometry. A total of 40 studies from 23 European countries provided 75 urine samples covering the whole range of concentrations. Conversion formulas for UIC derived from the gold-standard values were established by linear regression models and were used to postharmonize the studies by standardizing the UIC data of the individual studies. Results: In comparison with the EUthyroid gold-standard, mean UIC measurements were higher in 11 laboratories and lower in 10 laboratories. The mean differences ranged from -36.6% to 49.5%. Of the 40 postharmonized studies providing data for the standardization, 16 were conducted in schoolchildren, 13 in adults, and 11 in pregnant women. Median standardized UIC was
YR 2020
FD 2020-07-15
LK http://hdl.handle.net/10668/15645
UL http://hdl.handle.net/10668/15645
LA en
DS RISalud
RD Apr 5, 2025