TY - JOUR AU - Romano, Antonino AU - Oussalah, Abderrahim AU - Chery, Celine AU - Guéant-Rodriguez, Rosa-Maria AU - Gaeta, Francesco AU - Cornejo-Garcia, Jose-Antonio AU - Rouyer, Pierre AU - Josse, Thomas AU - Mayorga, Cristobalina AU - Torres, Maria-Jose AU - Guéant, Jean-Louis PY - 2021 DO - 10.1111/all.15147 UR - http://hdl.handle.net/10668/19893 T2 - Allergy AB - Nonimmediate (delayed)-allergic reactions to penicillins are common and some of them can be life-threatening. The genetic factors influencing these reactions are unknown/poorly known/poorly understood. We assessed the genetic predictors of a delayed... LA - en KW - HLA-DRB3 KW - amoxicillin KW - beta-lactams KW - drug allergy KW - genome-wide association KW - nonimmediate reactions KW - penicillins KW - Alleles KW - Drug Hypersensitivity KW - Genotype KW - HLA-DRB3 Chains KW - High-Throughput Nucleotide Sequencing KW - Humans KW - Hypersensitivity, Delayed KW - Hypersensitivity, Immediate KW - Penicillins TI - Next-generation sequencing and genotype association studies reveal the association of HLA-DRB3*02:02 with delayed hypersensitivity to penicillins. TY - research article VL - 77 ER -