TY - JOUR AU - Sonke, Gabe S AU - Hart, Lowell L AU - Campone, Mario AU - Erdkamp, Frans AU - Janni, Wolfgang AU - Verma, Sunil AU - Villanueva, Cristian AU - Jakobsen, Erik AU - Alba, Emilio AU - Wist, Erik AU - Favret, Anne M AU - Bachelot, Thomas AU - Hegg, Roberto AU - Wheatley-Price, Paul AU - Souami, Farida AU - Sutradhar, Santosh AU - Miller, Michelle AU - Germa, Caroline AU - Burris, Howard A PY - 2017 DO - 10.1007/s10549-017-4523-y UR - http://hdl.handle.net/10668/11714 T2 - Breast cancer research and treatment AB - Determine the efficacy and safety of first-line ribociclib plus letrozole in elderly patients with HR+, HER2- advanced breast cancer. 668 postmenopausal women with HR+, HER2- advanced breast cancer and no prior systemic therapy for advanced disease... LA - en KW - Breast cancer KW - CDK inhibitor KW - Elderly KW - Endocrine therapy KW - Hormone receptor-positive KW - Ribociclib KW - Aged KW - Aged, 80 and over KW - Aminopyridines KW - Antineoplastic Combined Chemotherapy Protocols KW - Biomarkers, Tumor KW - Breast Neoplasms KW - Disease-Free Survival KW - Female KW - Humans KW - Letrozole KW - Middle Aged KW - Nitriles KW - Purines KW - Receptor, ErbB-2 KW - Receptors, Estrogen KW - Receptors, Progesterone KW - Triazoles TI - Ribociclib with letrozole vs letrozole alone in elderly patients with hormone receptor-positive, HER2-negative breast cancer in the randomized MONALEESA-2 trial. TY - research article VL - 167 ER -