TY - JOUR AU - Bellmunt, Joaquim AU - Valderrama, Begoña P AU - Puente, Javier AU - Grande, Enrique AU - Bolós, M Victoria AU - Lainez, Nuria AU - Vázquez, Sergio AU - Maroto, Pablo AU - Climent, Miguel Ángel AU - Garcia Del Muro, Xavier AU - Arranz, José Ángel AU - Durán, Ignacio PY - 2022 DO - 10.1016/j.critrevonc.2022.103683 UR - http://hdl.handle.net/10668/22144 T2 - Critical reviews in oncology/hematology AB - Management of first-line advanced urothelial carcinoma (UC) has consisted during the past three decades in the administration of platinum-based chemotherapy followed by observation. Despite moderate to high response rates to first-line treatment, most... LA - en KW - Antibody drug-conjugate (ADC) KW - Avelumab KW - Bladder cancer KW - Checkpoint inhibitors (CPIs) KW - Platinum-based chemotherapy KW - Switch maintenance KW - Urothelial carcinoma (UC) KW - Carcinoma, Transitional Cell KW - Disease Management KW - Humans KW - Immunotherapy KW - Neoplasm Recurrence, Local KW - Urinary Bladder Neoplasms TI - Recent therapeutic advances in urothelial carcinoma: A paradigm shift in disease management. TY - research article VL - 174 ER -