TY  - JOUR
AU  - Pérez-Antón, Elena
AU  - Egui, Adriana
AU  - Thomas, M Carmen
AU  - Carrilero, Bartolomé
AU  - Simón, Marina
AU  - López-Ruz, Miguel Ángel
AU  - Segovia, Manuel
AU  - López, Manuel Carlos
PY  - 2021
DO  - 10.1371/journal.pntd.0009059
UR  - http://hdl.handle.net/10668/17104
T2  - PLoS neglected tropical diseases
AB  - Signs of senescence and the late stages of differentiation associated with the more severe forms of Chagas disease have been described in the Trypanosoma cruzi antigen-specific CD4+ T-cell population. However, the mechanisms involved in these...
LA  - en
KW  - Adult
KW  - Antibodies, Protozoan
KW  - Antiprotozoal Agents
KW  - CD4-Positive T-Lymphocytes
KW  - Chagas Disease
KW  - Female
KW  - Granzymes
KW  - Humans
KW  - Interferon-gamma
KW  - Male
KW  - Middle Aged
KW  - Nitroimidazoles
KW  - Perforin
KW  - Spain
KW  - Trypanosoma cruzi
KW  - Young Adult
TI  - A proportion of CD4+ T cells from patients with chronic Chagas disease undergo a dysfunctional process, which is partially reversed by benznidazole treatment.
TY  - research article
VL  - 15
ER  -