TY  - JOUR
AU  - Rada, Patricia
AU  - Pardo, Virginia
AU  - Mobasher, Maysa A
AU  - García-Martínez, Irma
AU  - Ruiz, Laura
AU  - González-Rodríguez, Águeda
AU  - Sanchez-Ramos, Cristina
AU  - Muntané, Jordi
AU  - Alemany, Susana
AU  - James, Laura P
AU  - Simpson, Kenneth J
AU  - Monsalve, María
AU  - Valdecantos, Maria Pilar
AU  - Valverde, Ángela M
PY  - 2017
DO  - 10.1089/ars.2017.7373
UR  - http://hdl.handle.net/10668/11747
T2  - Antioxidants & redox signaling
AB  - Sirtuin 1 (SIRT1) is a key player in liver physiology and a therapeutic target against hepatic inflammation. We evaluated the role of SIRT1 in the proinflammatory context and oxidative stress during acetaminophen (APAP)-mediated hepatotoxicity. SIRT1...
LA  - en
KW  - SIRT1
KW  - antioxidant defense
KW  - hepatotoxicity
KW  - inflammation
KW  - interleukin 1β
KW  - oxidative stress
KW  - paracetamol
KW  - Acetaminophen
KW  - Animals
KW  - Cell Death
KW  - Cells, Cultured
KW  - Humans
KW  - Inflammation
KW  - Liver
KW  - Macrophages
KW  - Male
KW  - Mice
KW  - Mice, Inbred C57BL
KW  - Oxidative Stress
KW  - RAW 264.7 Cells
KW  - Sirtuin 1
TI  - SIRT1 Controls Acetaminophen Hepatotoxicity by Modulating Inflammation and Oxidative Stress.
TY  - research article
VL  - 28
ER  -