RT Journal Article
T1 Patients Admitted to Three Spanish Intensive Care Units for Poisoning: Type of Poisoning, Mortality, and Functioning of Prognostic Scores Commonly Used.
A1 Banderas-Bravo, Maria Esther
A1 Arias-Verdu, Maria Dolores
A1 Macias-Guarasa, Ines
A1 Aguilar-Alonso, Eduardo
A1 Castillo-Lorente, Encarnación
A1 Perez-Costillas, Lucia
A1 Gutierrez-Rodriguez, Raquel
A1 Quesada-Garcia, Guillermo
A1 Rivera-Fernandez, Ricardo
K1 Poisoning
K1 Mortality
K1 Intensive Care Units
K1 Gravitation
K1 Glasgow Coma Scale
K1 Suicide
AB Objectives. To evaluate the gravity and mortality of those patients admitted to the intensive care unit for poisoning. Also, the applicability and predicted capacity of prognostic scales most frequently used in ICU must be evaluated. Methods. Multicentre study between 2008 and 2013 on all patients admitted for poisoning. Results. The results are from 119 patients. The causes of poisoning were medication, 92 patients (77.3%), caustics, 11 (9.2%), and alcohol, 20 (16,8%). 78.3% attempted suicides. Mean age was 44.42 ± 13.85 years. 72.5% had a Glasgow Coma Scale (GCS) ≤8 points. The ICU mortality was 5.9% and the hospital mortality was 6.7%. The mortality from caustic poisoning was 54.5%, and it was 1.9% for noncaustic poisoning (p< 0.001). After adjusting for SAPS-3 (OR:1.19 (1.02–1.39)) the mortality of patients who had ingested caustics was far higher than the rest (OR: 560.34 (11.64–26973.83)). T herewasconsiderablediscrepancybetweenmortalitypredictedbySAPS-3(26.8%)andobserved(6.7%)(Hosmer-Lemeshowtest: 𝐻=35.10; 𝑝 < 0.001). The APACHE-II (7,57%) and APACHE-III (8,15%) were no discrepancies. Conclusions. Admission to ICU for poisoning is rare in ourcountry. Medicationisthemostfrequentcause,butmortalityofcausticpoisoningishigher. APACHE-II and APACHE-III provide adequate predictions about mortality, while SAPS-3 tends to overestimate.
PB John Wiley & Sons
YR 2017
FD 2017-03-28
LK http://hdl.handle.net/10668/11149
UL http://hdl.handle.net/10668/11149
LA en
NO Banderas-Bravo ME, Arias-Verdú MD, Macías-Guarasa I, Aguilar-Alonso E, Castillo-Lorente E, Pérez-Costillas L, et al. Patients Admitted to Three Spanish Intensive Care Units for Poisoning: Type of Poisoning, Mortality, and Functioning of Prognostic Scores Commonly Used. Biomed Res Int. 2017;2017:5261264
NO T he authors thank the Andalusian Public Foundation for Health and Biomedicine Research in M´ alaga for making substantial contributions to conception and for important role of the funding (Project SAS PI-0157/2007). They also thank Emilia Civeira Murillo M.D. (Coordinator of the Toxicology Working Group of the Spanish Society of Intensive Care Medicine and Coronary Units) and the rest of the members of Toxicology Working Group of the Spanish Society of Intensive Care Medicine and Coronary Units (SEMICYUC) for their help and support given for the realization of this manuscript.
DS RISalud
RD Jul 1, 2025