TY - JOUR AU - Guerrero-Martínez, Jose A. AU - Ceballos-Chávez, María AU - Koehler, Florian AU - Peiró, Sandra AU - Reyes, Jose C. PY - 2020 DO - 10.1038/s41467-020-19877-5 UR - http://hdl.handle.net/10668/3679 T2 - Nature Communications AB - The Transforming Growth Factor-β (TGFβ) signaling pathway controls transcription by regulating enhancer activity. How TGFβ-regulated enhancers are selected and what chromatin changes are associated with TGFβ-dependent enhancers regulation are still... LA - en PB - Springer Nature KW - Chromatin KW - Gene expression regulation KW - Genome KW - Transforming growth factor beta KW - Enhancer elements, genetic KW - Genome informatics KW - Transcriptional regulatory elements KW - Cromatina KW - Regulación de la expresión génica KW - Genoma KW - Factor de crecimiento transformador beta KW - Elementos de facilitación genéticos KW - Medical Subject Headings::Organisms::Eukaryota::Animals KW - Medical Subject Headings::Anatomy::Cells::Cellular Structures::Intracellular Space::Cell Nucleus::Cell Nucleus Structures::Intranuclear Space::Chromosomes::Chromosome Structures::Chromatin KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Processes::Gene Expression Regulation KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Structures::Genome KW - Medical Subject Headings::Anatomy::Cells::Epithelial Cells::HEK293 Cells KW - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans KW - Medical Subject Headings::Anatomy::Cells::Cells, Cultured::Cell Line::Cell Line, Tumor::MCF-7 Cells KW - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Mice KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Structures::Genome::Genome Components::Genes::Multigene Family KW - Medical Subject Headings::Chemicals and Drugs::Nucleic Acids, Nucleotides, and Nucleosides::Nucleic Acids::RNA::RNA, Messenger KW - Medical Subject Headings::Chemicals and Drugs::Biological Factors::Intercellular Signaling Peptides and Proteins::Transforming Growth Factors KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Structures::Genome::Genome Components::Genes::Gene Components::Regulatory Elements, Transcriptional::Enhancer Elements, Genetic TI - TGFβ promotes widespread enhancer chromatin opening and operates on genomic regulatory domains TY - research article ER -