%0 Journal Article
%A Plaza, Vicente
%A Fernández-Rodríguez, Concepción
%A Melero, Carlos
%A Cosío, Borja G
%A Entrenas, Luís Manuel
%A de Llano, Luis Pérez
%A Gutiérrez-Pereyra, Fernando
%A Tarragona, Eduard
%A Palomino, Rosa
%A López-Viña, Antolín
%A TAI Study Group
%T Validation of the 'Test of the Adherence to Inhalers' (TAI) for Asthma and COPD Patients.
%D 2015
%U http://hdl.handle.net/10668/10038
%X To validate the 'Test of Adherence to Inhalers' (TAI), a 12-item questionnaire designed to assess the adherence to inhalers in patients with COPD or asthma. A total of 1009 patients with asthma or COPD participated in a cross-sectional multicenter study. Patients with electronic adherence ≥80% were defined as adherents. Construct validity, internal validity, and criterion validity were evaluated. Self-reported adherence was compared with the Morisky-Green questionnaire. Factor analysis study demonstrated two factors, factor 1 was coincident with TAI patient domain (items 1 to 10) and factor 2 with TAI health-care professional domain (items 11 and 12). The Cronbach's alpha was 0.860 and the test-retest reliability 0.883. TAI scores correlated with electronic adherence (ρ=0.293, p=0.01). According to the best cut-off for 10 items (score 50, area under the ROC curve 0.7), 569 (62.5%) patients were classified as non-adherents. The non-adherence behavior pattern was: erratic 527 (57.9%), deliberate 375 (41.2%), and unwitting 242 (26.6%) patients. As compared to Morisky-Green test, TAI showed better psychometric properties. The TAI is a reliable and homogeneous questionnaire to identify easily non-adherence and to classify from a clinical perspective the barriers related to the use of inhalers in asthma and COPD.
%K anti-asthmatic agents, administration and dosage
%K inhalers
%K medication adherence
%K medication non-adherence
%K pulmonary disease, chronic obstructive, drug therapy
%K questionnaires
%K validation studies
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