%0 Journal Article
%A Anguita-Ruiz, Augusto
%A Plaza-Diaz, Julio
%A Ruiz-Ojeda, Francisco Javier
%A Ruperez, Azahara I
%A Leis, Rosaura
%A Bueno, Gloria
%A Gil-Campos, Mercedes
%A Vazquez-Cobela, Rocio
%A Cañete, Ramon
%A Moreno, Luis A
%A Gil, Angel
%A Aguilera, Concepcion Maria
%T X chromosome genetic data in a Spanish children cohort, dataset description and analysis pipeline.
%D 2019
%U http://hdl.handle.net/10668/14281
%X X chromosome genetic variation has been proposed as a potential source of missing heritability for many complex diseases, including obesity. Currently, there is a lack of public available genetic datasets incorporating X chromosome genotype data. Although several X chromosome-specific statistics have been developed, there is also a lack of readily available implementations for routine analysis. Here, we aimed: (1) to make public and describe a dataset incorporating phenotype and X chromosome genotype data from a cohort of 915 normal-weight, overweight and obese children, and (2) to deeply describe a whole implementation of the special X chromosome analytic process in genetics. Datasets and pipelines like this are crucial to get familiar with the steps in which X chromosome requires special attention and may raise awareness of the importance of this genomic region.
%K Genetic Variation
%K Child
%K Chromosomes, Human, X
%K Female
%K Gene Frequency
%~