TY - JOUR AU - Recacha, E AU - Machuca, J AU - Diaz-Diaz, S AU - Garcia-Duque, A AU - Ramos-Guelfo, M AU - Docobo-Perez, F AU - Blazquez, J AU - Pascual, A AU - Rodriguez-Martinez, J M PY - 2019 DO - 10.1093/jac/dky407 UR - http://hdl.handle.net/10668/13098 T2 - The Journal of antimicrobial chemotherapy AB - Suppression of the SOS response has been proposed as a therapeutic strategy for potentiating quinolones against susceptible, low-level quinolone-resistant (LLQR) and resistant Enterobacteriaceae. To monitor the functionality of the SOS response in the... LA - en PB - Oxford University Press KW - Respuesta SOS KW - Resistencia a quinolonas KW - Escherichia coli KW - Mutación KW - Concentración preventiva de mutantes KW - Aptitud bacteriana KW - Formación de biopelículas KW - Efecto postantibiótico KW - Evolución de la resistencia KW - Anti-Bacterial Agents KW - Biofilms KW - DNA-Binding Proteins KW - Drug Resistance, Bacterial KW - Escherichia coli KW - Escherichia coli Proteins KW - Gene Deletion KW - Microbial Sensitivity Tests KW - Rec A Recombinases KW - SOS Response, Genetics KW - Spatio-Temporal Analysis TI - Suppression of the SOS response modifies spatiotemporal evolution, post-antibiotic effect, bacterial fitness and biofilm formation in quinolone-resistant Escherichia coli. TY - research article VL - 74 ER -