RT Journal Article
T1 Trends in Mortality Due to Myocardial Infarction, Stroke, and Pulmonary Embolism in Patients Receiving Dialysis.
A1 Ocak, Gurbey
A1 Boenink, Rianne
A1 Noordzij, Marlies
A1 Bos, Willem Jan W
A1 Vikse, Bjorn E
A1 Cases, Aleix
A1 Kerschbaum, Julia
A1 Helve, Jaakko
A1 Nordio, Maurizio
A1 Arici, Mustafa
A1 Mercadal, Lucile
A1 Wanner, Christoph
A1 Palsson, Runolfur
A1 Hommel, Kristine
A1 De Meester, Johan
A1 Kostopoulou, Myrto
A1 Santamaria, Rafael
A1 Rodrigo, Emilio
A1 Rydell, Helena
A1 Bell, Samira
A1 Massy, Ziad A
A1 Jager, Kitty J
A1 Kramer, Anneke
AB During the past decades, improvements in the prevention and management of myocardial infarction, stroke, and pulmonary embolism have led to a decline in cardiovascular mortality in the general population. However, it is unknown whether patients receiving dialysis have also benefited from these improvements. To assess the mortality rates for myocardial infarction, stroke, and pulmonary embolism in a large cohort of European patients receiving dialysis compared with the general population. In this cohort study, adult patients who started dialysis between 1998 and 2015 from 11 European countries providing data to the European Renal Association Registry were and followed up for 3 years. Data were analyzed from September 2020 to February 2022. Start of dialysis. The age- and sex-standardized mortality rate ratios (SMRs) with 95% CIs were calculated by dividing the mortality rates in patients receiving dialysis by the mortality rates in the general population for 3 equal periods (1998-2003, 2004-2009, and 2010-2015). In total, 220 467 patients receiving dialysis were included in the study. Their median (IQR) age was 68.2 (56.5-76.4) years, and 82 068 patients (37.2%) were female. During follow-up, 83 912 patients died, of whom 7662 (9.1%) died because of myocardial infarction, 5030 (6.0%) died because of stroke, and 435 (0.5%) died because of pulmonary embolism. Between the periods 1998 to 2003 and 2010 to 2015, the SMR of myocardial infarction decreased from 8.1 (95% CI, 7.8-8.3) to 6.8 (95% CI, 6.5-7.1), the SMR of stroke decreased from 7.3 (95% CI, 7.0-7.6) to 5.8 (95% CI, 5.5-6.2), and the SMR of pulmonary embolism decreased from 8.7 (95% CI, 7.6-10.1) to 5.5 (95% CI, 4.5-6.6). In this cohort study of patients receiving dialysis, mortality rates for myocardial infarction, stroke, and pulmonary embolism decreased more over time than in the general population.
YR 2022
FD 2022-04-01
LK http://hdl.handle.net/10668/20618
UL http://hdl.handle.net/10668/20618
LA en
DS RISalud
RD Apr 18, 2025